You may see this Error in the out.log File:

I. 08/08 06:20:18. Database recovery in progress
I. 08/08 06:20:18.     Last checkpoint at Mon Aug 08 2011 06:13
I. 08/08 06:20:18.     Transaction log: sem5.log…
I. 08/08 06:20:18. Starting checkpoint of „sem5“ (sem5.db) at Mon Aug 08 2011 06:20
I. 08/08 06:20:18. Finished checkpoint of „sem5“ (sem5.db) at Mon Aug 08 2011 06:20
E. 08/08 06:20:18. *** ERROR *** Assertion failed: 100904[sem5] (11.0.1.2472)
Failed to redo a database operation (id=4, page_no=0x8fc9, offset=0xbac) – Error: Cannot access file ‚E:\Symantec Endpoint Protection Manage
I. 08/08 06:20:18. Recovery complete
E. 08/08 06:20:18. Internal database error *** ERROR *** Assertion failed: 100904[sem5] (11.0.1.2472) Failed to redo a database operation (id=4, page_no=0x8fc9, offset=0xbac) – Error: Cannot access file ‚E:\Symantec Endpoint Protection Manage — transaction rolled back
I. 08/08 06:20:18. Database server shutdown due to startup error

%DRIVE%\Program Files\Symantec\Symantec Endpoint Protectuion Manager\tomcat\etc\conf.properties

Add:

scm.log.loglevel=FINEST

scm.mail.troubleshoot=1

When starting SEPM COnsole you will get the Message „Unexpected  server error. Errorcode: 0x10010000“ but will be sucessfully logged in. You will have black screens at Home, Monitors and Reports.

There my be many reasony for that described at the Symantec Support Page. I have one more:

Look at the …\Symantec Endpoint Protection Manager\apache\logs\error-……..log. In a large Environment you may get this Message :
[Thu Aug 30 08:45:49 2012] [warn] [client x.x.x.x] mod_fcgid: stderr: PHP Warning:  Unknown: POST Content-Length of 8440038 bytes exceeds the limit of 8388608 bytes in Unknown on line 0

Add the following line to  …\Symantec Endpoint Protection Manager\php\php.ini:
post_max_size=xxxM where xxx is the SIze you want it to be, should be more than the POST Content length in the Error Message

Restart „Symantec Endpoint Protection Manager Webserver“ Service