When starting SEPM COnsole you will get the Message „Unexpected  server error. Errorcode: 0x10010000“ but will be sucessfully logged in. You will have black screens at Home, Monitors and Reports.

There my be many reasony for that described at the Symantec Support Page. I have one more:

Look at the …\Symantec Endpoint Protection Manager\apache\logs\error-……..log. In a large Environment you may get this Message :
[Thu Aug 30 08:45:49 2012] [warn] [client x.x.x.x] mod_fcgid: stderr: PHP Warning:  Unknown: POST Content-Length of 8440038 bytes exceeds the limit of 8388608 bytes in Unknown on line 0

Add the following line to  …\Symantec Endpoint Protection Manager\php\php.ini:
post_max_size=xxxM where xxx is the SIze you want it to be, should be more than the POST Content length in the Error Message

Restart „Symantec Endpoint Protection Manager Webserver“ Service